SNARE 依存性の exocytosis を止める
Amphiphysin mutation
Drosophila Amphiphysin functions during synaptic Fasciclin II membrane cycling
Mathew D, Popescu A and Budnik V
J. Neurosci. 23, 10710-10716 (2003)
UAS-TNT (tetanus toxin) cleaves syb.
Dominant negative form of NSF
E329Q point mutation reduces ATPase activity and transport from golgi. This form act as a dominant negative, since NSF functions as a multimer
SNARE-dependent signaling at the Drosophila wing margin.
Stewart BA, Mohtashami M, Zhou L, Trimble WS, Boulianne GL.
Dev Biol. 234, 13-23.(2001)
N-ethylmaleimide-sensitive fusion protein: a trimeric ATPase whose hydrolysis of ATP is required for membrane fusion.
Whiteheart SW, Rossnagel K, Buhrow SA, Brunner M, Jaenicke R, Rothman JE.
J Cell Biol. 126, 945-54. (1994)