SNARE 依存性の exocytosis を止める

Amphiphysin mutation

Drosophila Amphiphysin functions during synaptic Fasciclin II membrane cycling

Mathew D, Popescu A and Budnik V
J. Neurosci. 23, 10710-10716 (2003)

Dominant negative form of NSF

E329Q point mutation reduces ATPase activity and transport from golgi. This form act as a dominant negative, since NSF functions as a multimer

SNARE-dependent signaling at the Drosophila wing margin.

Stewart BA, Mohtashami M, Zhou L, Trimble WS, Boulianne GL.
Dev Biol. 234, 13-23.(2001)

N-ethylmaleimide-sensitive fusion protein: a trimeric ATPase whose hydrolysis of ATP is required for membrane fusion.

Whiteheart SW, Rossnagel K, Buhrow SA, Brunner M, Jaenicke R, Rothman JE.
J Cell Biol. 126, 945-54. (1994)